Metastasis of Colorectal Cancer
Nicole Beauchemin, Jacques Huot
Springer Science & Business Media, Jul 23, 2010 - Medical - 416 pages
Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths.
This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatment.
Each chapter has been contributed by leaders in the field. A key feature is that it connects with a large readership including students, fundamentalists and clinicians. Another specific feature of the book is that the chapters are written in a didactic and illustrative fashion. These characteristics coupled with the choice of the topics and authors, makes this book a reference in the field. It represents an essential acquisition for medical libraries, clinicians as well as medical and graduate students.
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2 Physiopathology of Colorectal Metastasis
3 The Genetics of Colorectal Cancer
4 Epigenetics of Colorectal Cancer
5 CancerInitiating Cells in Colorectal Cancer
6 EpithelialMesenchymal Transition in Colorectal Cancer
7 Cell Adhesion Molecules in Colon Cancer Metastasis
8 Epithelial Cell Signalling in Colorectal Cancer Metastasis
9 Angiogenesis and Lymphangiogenesis in Colon Cancer Metastasis
10 Role of the Host Inflammatory Response in Colon Carcinoma Initiation Progression and Liver Metastasis
11 Molecular Prognostic Markers in Colon Cancer
12 The Sentinel Lymph Node and Staging of Colorectal Cancer
13 Treatment of Colorectal Cancer
14 Diagnosis and Treatment of Rectal Cancer
15 Future Directions