Metastasis of Colorectal Cancer

Front Cover
Nicole Beauchemin, Jacques Huot
Springer Science & Business Media, Jul 23, 2010 - Medical - 416 pages

Colorectal cancer is the third most common cancer worldwide, and in many parts of the western world, it is the second leading cause of cancer-related deaths.

This book covers colon cancer metastasis from the most fundamental aspects to clinical practice. Major topics include physiopathology, genetic and epigenetic controls, cancer initiating cells, epithelial-mesenchymal transition, growth factors and signalling, cell adhesion, natures of liver metastasis, angiogenesis and lymphangiogenesis, inflammatory response, prognostic markers, sentinel node and staging, and finally diagnosis and treatment.

Each chapter has been contributed by leaders in the field. A key feature is that it connects with a large readership including students, fundamentalists and clinicians. Another specific feature of the book is that the chapters are written in a didactic and illustrative fashion. These characteristics coupled with the choice of the topics and authors, makes this book a reference in the field. It represents an essential acquisition for medical libraries, clinicians as well as medical and graduate students.

 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

An Overview
1
2 Physiopathology of Colorectal Metastasis
33
3 The Genetics of Colorectal Cancer
65
4 Epigenetics of Colorectal Cancer
101
5 CancerInitiating Cells in Colorectal Cancer
126
6 EpithelialMesenchymal Transition in Colorectal Cancer
147
7 Cell Adhesion Molecules in Colon Cancer Metastasis
173
8 Epithelial Cell Signalling in Colorectal Cancer Metastasis
205
9 Angiogenesis and Lymphangiogenesis in Colon Cancer Metastasis
242
10 Role of the Host Inflammatory Response in Colon Carcinoma Initiation Progression and Liver Metastasis
289
11 Molecular Prognostic Markers in Colon Cancer
320
12 The Sentinel Lymph Node and Staging of Colorectal Cancer
343
13 Treatment of Colorectal Cancer
359
14 Diagnosis and Treatment of Rectal Cancer
389
15 Future Directions
408
Index
412

Other editions - View all

Common terms and phrases

Bibliographic information