Methods for Genetic Risk Assessment

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CRC Press, Jan 11, 1994 - Science - 272 pages
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Genetic disease contributes to a major portion of our health care costs. While most of the human genetic burden is transmitted from generation to generation, environmental chemicals capable of reacting with germ cell DNA could produce new mutations, resulting in an even greater genetic liability for the next generation. The potential impact of environmental mutagens on the health and viability of other living things is important to consider as well.
Methods for Genetic Risk Assessment features contributions from international experts to provide a comprehensive review of the current status of genetic risk assessment. You'll learn about various methods and strategies for when and how to conduct genetic risk assessments on human populations. You will also learn about the potential effects of environmental genotoxins on nonhuman organisms. Topics considered include:

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Assessment of Exposures
Methods for Dose and Effect Assessment
Risk Characterization Strategies
Monitoring Environmental Genotoxicants

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Page 237 - Application of ShortTerm Bioassays in the Fractionation and Analysis of Complex Environmental Mixtures (MD Waters, S.
Page 230 - Sister chromatid exchanges, indices of human chromosome damage and repair: detection by fluorescence and induction by mitomycin C.

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