Microbes and Malignancy: Infection as a Cause of Human Cancers
Oxford University Press, 1999 - Medical - 465 pages
Historically, the study of infection has focused on acute illnesses and their treatment. Infection, however, is not simply an acute process; microbial agents thrive in the human body throughout life. The unrecognized, intimate relationship we share with microorganisms is a critical factor in longevity and health. In recent years, it has become apparent that some cancers may be attributable to underlying chronic infection. Fortunately, infectious diseases are often treatable or preventable. Also, the composition of infectious agents is far less complex than that of humans. Thus the link between infection and cancer may offer insight into the pathogenesis and prevention of all cancers. This book, authored by some of the world's leaders in microbiology, virology, biochemistry, and pathology, provides an overview of oncogenic mechanisms imputed to infection. Individual chapters examine the epidemiologic, clinical and molecular links between specific infectious agents and cancer, and address methods of disease prevention. Microbiologists, cancer biologists, pathologists, oncologists, and infectious disease specialists interested in the etiology of malignancy will find this book an indispensable addition to their libraries.
What people are saying - Write a review
We haven't found any reviews in the usual places.
MECHANISMS OF INFECTIONINDUCED
Chronic Inflammation Mutation and Cancer
14 other sections not shown
Acad Sci USA acid activity agents animals antibodies antigen associated B-cell bacterial bile bladder cancer c-myc Cancer Res carcinogenesis carcinogenic cause cell lines cellular cervical cholangiocarcinoma chromosome chronic clinical clonal colon cancer cytotoxic detected disease DNA damage duct encodes epidemiological epithelial cells Epstein-Barr virus expression formation function gastric cancer gastric lymphoma gene genetic genome growth haematobium hamsters Hausen H HCV infection Helicobacter pylori hepadnavirus hepatitis B virus hepatocellular carcinoma herpesvirus human papillomavirus immune immunodeficiency incidence increased induced inflammation inflammatory integration Kaposi's sarcoma KSHV lesions leukemia lipid liver fluke LMP1 lymphocytes macrophages malignant MALT lymphoma mechanisms mice molecular mucosal mutagenic mutations Natl Acad Sci nitric oxide occur oncogenic parasite pathogens patients populations Proc Natl Acad protein pylori infection reactive receptor replication response role schistosomal schistosomiasis sequences sinensis specific squamous studies tion tissue transcription transformation tumor urinary viral DNA Virol viruses vitro viverrini vivo