Minicircle and Miniplasmid DNA Vectors: The Future of Non-viral and Viral Gene Transfer

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Martin Schleef
John Wiley & Sons, Feb 14, 2013 - Science - 300 pages
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This first title on the topic provides complete coverage, including the molecular basis, production and possible biomedical applications. Written by the most prominent academic researchers in the field as well as by researchers at one of the world's leading companies in industrial production of minicircle DNA, this practical book is aimed at everyone who is directly or indirectly involved in the development of gene therapies.
 

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Contents

Preface
Selection by RNARNA Interaction Maximally
PlasmidBased Medicinal Products Focus
Plasmid DNA Concatemers Influence
Analytical Tools in Minicircle Production
Utilizing Minicircle Vectors for the Episomal
Replicating Minicircles Overcoming
Magnetofection of Minicircle DNA Vectors
MinicircleBased Vectors for Nonviral Gene
Episomal Expression of Minicircles
TissueTargeted Gene Electrodelivery
Increased Efficiency of Minicircles Versus
Index
Copyright

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About the author (2013)

Dr. Martin Schleef studied Biology at the Universities of Wurzburg and Bielefeld, Germany and holds a PhD from the University of Bielefeld.
Martin Schleef received post-doctoral training from the Institut Pasteur Paris, France. He joined QIAGEN GmbH, Hilden, Germany in 1994 and is co-founder and CEO of PlasmidFactory in Bielefeld since 2000.

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