This book is the eagerly awaited second edition of the best-selling Mitochondria, a book widely acknowledged as the first modern, truly comprehensive authored work on the important, scientifically fundamental topic of the cellular organelles known as mitochondria. This new edition brings readers completely up to date on the many significant findings that have occurred in the eight years since the book was first published. As in that seminal first edition, the second edition tackles the biochemistry, genetics, and pathology of mitochondria in different organisms. The new edition provides thorough updates of all literature concerning this vital organelle, its functions, ongoing research surrounding it, and its importance vis-à-vis a broad range of issues in cellular and molecular biology. The book includes detailed descriptions of current and developing technologies around mitochondrial research and discovery, and highlights subjects that are growing, such as the use of proteomics. -- Publisher.
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Evolutionary Origin of Mitochondria
Structure and Morphology Integration into the Cell
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Acad Acta activity amino acid apoptosis assembly ATP synthase bacterial binding Biochem biogenesis Biol Biophys cardiolipin cells cerevisiae Chem chondrial cloned cluster codon complex complex III cristae cycle cytochrome cytoplasmic cytosol D-loop deletions detailed discussion DNA replication electron transport chain encoded enzyme eukaryotes factors Fe—S Figure function fusion genetic glucose heme human identified import inhibitors inner membrane integral membrane proteins interaction introns isolated lipid mammalian matrix mechanism membrane potential membrane proteins metabolism mito mitochon mitochondrial diseases mitochondrial DNA mitochondrial genome mitochondrial membrane mitochondrial protein molecular molecules mRNA mt genome mtDNA mutations NADH Natl nuclear genes nucleotide observed organelle organisms outer membrane oxidase oxidative phosphorylation oxygen pathway peptides plant plasmid polymerase Proc prokaryotic proton reactions recombination reference region respiration ribosomal role rRNA Scheffler sequence specific structure studies subcomplex substrate subunits synthesis tion tissue transcription translocation tRNA ubiquinone vitro yeast
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Progress in Nucleic Acid Research and Molecular Biology, Volume 77
Limited preview - 2004