Mobile DNA: Finding Treasure in Junk
This book thoroughly reviews our current scientific understanding of the significant role that mobile genetic elements play in the evolution and function of genomes and organisms–from plants and animals to humans. Highly-regarded geneticist Haig Kazazian offers an accessible intellectual history of the field’s research strategies and concerns, explaining how advances opened up new questions, and how new tools and capabilities have encouraged progress in the field.
Kazazian introduces the key strategies and approaches taken in leading laboratories (including his own) to gain greater insight into the large proportion of our genome that derives from mobile genetic elements, including viruses, plasmids, and transposons. He also presents intriguing insights into long-term research strategies that may lead to an even deeper understanding.
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DNA Transposons Chapter 4 Mobile DNA of Model Organisms Chapter 5 Exceptional Scientists Working on Mobile DNA in Lower Organisms
Role of Bioinformatics in Genome Analysis
Welcome to the Wonderful World of LINEs
An Experimental Breakthrough
The Independent Canadian
The Musician Scientist
Young Ladies in the Back
The Brilliant Young Lady from China Chapter 22 Hirokis Big Surprises Chapter 23 A Young Man with a Purpose
Other Mobile DNA in Mammalian Genomes Chapter 25 Effects of Retrotransposons on Mammalian Genomes
Host Factors Involved in L1 Retrotransposition
Why Mobile DNA?
Reverse Transcriptase to the Rescue
A Quirk of L1 ElementsA Lousy 3 End Is Important for Genome Evolution
A Tour de Force from Tom Eickbush
I dont believe all those colonies represent retrotransposition events
L1 Encodes an Endonuclease
The Mayor and the Frenchman