Molecular Aspects of Neurodegeneration and Neuroprotection

Front Cover
Akhlaq A. Farooqui, Tahira Farooqui
Bentham Science Publishers, Jan 1, 2011 - Science - 146 pages
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Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. for example, in Alzheimer disease, neuronal degeneration occurs in the nucleus basalis, whereas in Parkinson disease, neurons in the substantia nigra die. the most severely affected neurons in Huntington disease are striatal medium spiny neurons. the neuronal populations that are lost in neurodegenerative diseases modulate functions such as controlling movements, processing sensory information, memory, and making decisions. Although, the molecular mechanism of neurodegeneration remains unknown, but excitotoxicity, inflammation, and oxidative stress may contribute to neural cell demise independently or synergistically.The purpose of this E-book is to present readers with cutting edge and comprehensive information on molecular aspects of neurodegenerative diseases and neuroprotection in a manner that is useful not only to students and teachers, but also to researchers and physicians.
 

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Contents

Chapter 01
1
Chapter 02
10
Chapter 03
23
Chapter 04
39
Chapter 05
50
Chapter 06
62
Chapter 07
72
Chapter 08
90
Chapter 09
102
Chapter 10
121
Chapter 11
132
Index
140

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