Molecular Biology and Pathology: A Guidebook for Quality Control

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Daniel H. Farkas
Academic Press, Dec 2, 2012 - Science - 326 pages
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This is the first handbook to provide an all-in-one guide to establishing molecular biology protocols with requisite quality control. Molecular Biology and Pathology will help professionals sift through the incredible wealth of information available on molecular biology, specifically as it relates to the clinical arena of molecular pathology. This handbook provides excellent training information, and the concern of safety is discussed extensively. The handbook can serve as a primer and reference for those interested in the technical topics described, including the brief discussion of DNA banking. Quality Control (QC) suggestions are also presented.
 

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Contents

Chapter 1 Establishing a Clinical Molecular Biology Laboratory
1
Chapter 2 Safety in the Molecular Biology Laboratory
39
Chapter 3 Specimen Procurement Processing Tracking and Testing by the Southern Blot
51
Chapter 4 Quality Control of the BT Cell Gene Rearrangement Test
77
Clinical Perspectives and Quality Control
103
Chapter 6 Human Papillomavirus DNA Detection and Typing
123
Chapter 7 Quality Control of the Polymerase Chain Reaction
149
A Clinical Laboratory Perspective
159
Current Diagnostics
187
Chapter 10 Quality Control in DNA Profiling Tests
201
Chapter 11 Incorporating Molecular Pathology into Medical Technology Training Programs
217
Appendix 1 Procedure Manual for the BT Cell Gene Rearrangement Test and bar Analysis
233
Appendix 2 Quality Control Documentation
287
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