Molecular Biology of the Skin: The Keratinocyte
Michael Darmon, Miroslav Blumenberg
Academic Press, Dec 2, 2012 - Science - 291 pages
Molecular Biology of the Skin: The Keratinocyte comprehensively reviews the major aspects of keratinocyte and epidermal differentiation, physiology, and pathology, primarily focusing on the molecular aspects. This exciting new resource discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatological pathology. The volume also highlights areas of genetic disease, new animal models to help in understanding dermatological disorders, and gene therapy using skin as a target. W.W. Franke, a pioneer in the study of the molecular biology of keratins, has written the foreword for the book.
Molecular Biology of the Skin: The Keratinocyte is intended for use by dermatologists and basic researchers in cell and developmental biology. It will also be valuable for surgeons and other clinicians as well as researchers in gene therapy, virology, and pharmacology.
* Reviews keratinocyte (and epidermal) differentiation. physiology, and pathology, focusing on the molecular aspects
* -Discusses keratin genes, retinoic acid, and the use of transgenic animals in the study of dermatalogical pathology
* -Highlights genetic disease, new animal models, and gene therapy
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Chapter 2 Murine Epidermal Keratins
Chapter 3 Phenotypic Expression and Processing of Filaggrin in Epidermal Differentiation
A Key Structure of Terminally Differentiating Keratinocytes
Chapte 5 Loricrin
Chapter 6 Retinoic Acid in Epithelial and Epidermal Differentiation
Other editions - View all
Acad activity amino acid antibodies basal binding Biochem bovine Ca2+ calcium Cancer carcinoma cells cDNA Cell Biol cell lines cellular cervical Characterization Chem chromosome cornified cornified envelope crosslinking cultured human cultured keratinocytes cytokeratin Darmon Dermatol domains E7 protein embryonic encoding envelope formation enzyme epidermal cells epidermal differentiation epidermal keratin epidermal transglutaminase epithelium filaggrin Fuchs function gene expression gene therapy genetic genome glutaminase Green Hohl human keratin human keratinocytes human papillomavirus human papillomavirus type induced intermediate filament intron Invest involucrin keratin expression keratin genes keratinocytes layers loricrin markers Mehrel molecular mouse epidermis mRNA murine mutations Natl normal oncogene papillomas peptide phosphorylation precursor Proc profilaggrin promoter protein region regulation retinoic acid receptor retinoids Rice Roop Schweizer specific squamous Steinert stratum corneum structure suprabasal synthesis tion tissue transcription factors transformation transgenic transgenic mice tumors type I keratin viral Virol vitamin vitro vivo Yuspa