Molecular Mechanisms of Fanconi Anemia

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Shamim Ahmad, Sandra Kirk
Springer Science & Business Media, Mar 6, 2007 - Science - 121 pages

Molecular Mechanisms of Fanconi Anemia will give research students a platform for further investigation, and act as a source of information regarding experimental design. Clinicians will find this title useful for its comprehensive description of Fanconi Anemia and information on the latest molecular theories underlying its causes.

 

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Contents

Clinical Features of Fanconi Anaemia
1
The Genetic Basis of Fanconi Anemia
13
The FANCA Gene and Its Products
28
The FANCC Gene and Its Products
36
The FANC B E F and G Genes and Their Products
54
FANCD1BRCA2 and FANCD2
61
The FINC Genome Surveillance Complex
67
Other Proteins and Their Interactions with FA Gene Products
74
Therapy for Fanconi Anemia
92
Mutational Analyses of Fanconi Anemia Genes
103
15
115
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