Molecular Pathology in Clinical Practice

Front Cover
Debra G.B. Leonard
Springer Science & Business Media, Dec 21, 2006 - Medical - 600 pages

Molecular Pathology In Clinical Medicine is an authoritative, comprehensive textbook that provides the general pathologist in clinical practice, as well as residents and fellows during their training, with the current standard in molecular testing. The text is divided into 8 sections, as defined by the molecular pathology specialty board: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, HLA typing, identity testing, and laboratory management. The book integrates the latest advancements in the field with the basic principles and practical applications. Each chapter discusses the clinical significance of each diagnostic test, available assays, quality control and lab issues, interpretation, and reasons for testing. Chapters cover such topics as HIV, herpes, hepatitis, deafness, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. 189 illustrations, 45 of them in full-color, illustrate the principles outlined in the text. This textbook is a classic in the making and a must-have reference to meet the needs of every pathologist, resident and fellow.

 

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Contents

Molecular Pathology Methods
15
Genetics
42
Bayesian Analysis
59
Developmental Disabilities
73
Neuromuscular Diseases
87
Fibroblast Growth Factor ReceptorRelated Skeletal Disorders
109
Deafness
125
13
151
Myeloproliferative Disorders and Myelodysplastic Syndromes
383
207
396
Infectious Diseases
397
Hepatitis B and C Viruses
411
215
423
Viral Infections in Transplant Patients
425
Viral Infections of the Central Nervous System
437
Sexually Transmitted Diseases
447

14
161
15
179
16
191
Inherited Cancers
204
Neibergs and Amy T Massey
215
Thorland and Stephen N Thibodeau
223
Karen Stephens
243
Finkelstein and Frank S Lieberman
251
Catherine Stolle
263
Halling Sarcomas
279
Kaul
305
Microarray Studies Beyond Histology
313
Neoplastic Hematopathology
319
Acute Lymphoblastic Leukemia
337
BCell Lymphomas
349
TCell Lymphomas
365
Lymphoproliferations of Immunodeficiency
373
Respiratory Pathogens
459
223
466
Bacterial Pathogens
471
Mycobacterial Infections
481
Identity Testing
490
Parentage and Relationship Testing
507
Assessment of Chimerism in the Setting of Allogeneic Hematopoietic
517
233
528
Specimen Identification Through DNA Analysis
533
Molecular HLA Typing
541
Laboratory Management Issues
551
243
574
From Research to Clinical Practice
577
251
581
Index
583
299
590
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