Molecular and Cell Biological Aspects of Gastroenteropancreatic Neuroendocrine Tumor Disease, Volume 733

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Bertram Wiedenmann
New York Academy of Sciences, Jan 1, 1994 - Medical - 535 pages
New molecular and cell biological approaches in the fields of neurobiology and neuroendocrinology have identified a large number of molecules that can be assigned structurally and functionally to various subcellular structures, such as secretory vesicles, the Golgi complex, the trans-Golgi network, and endosomes. It has become evident that neurons and neuroendocrine cells share many properties, such as the expression of very similar secretory vesicles and molecules, including cell adhesion molecules, neurotransmitters, hormones, neurotransmitter-receptors and hormone-receptors. Various molecules discovered and characterised in basic research have been found to be increasingly applicable for improved diagnosis and therapy of neuroendocrine tumour disease. This volume reviews current research in both basic science and clinical research from the viewpoint of its direct applicability to clinical medicine.

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Contents

Classification of Normal and Neoplastic Neuroendocrine Cells By Gunter
18
Pathogenesis and Diagnosis of Enterochromaffinlike Cell Tumors
24
Transcriptional Basis of
36
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