Molecular Aspects of Dermatology
G. C. Priestley
Wiley, Oct 21, 1993 - Medical - 230 pages
Skin diseases remain a major cause of embarassment, discomfort and incapacity. This book provides a timely and authoritative review of recent developments in the study of the skin and its component molecules. As research begins to move from the protein to the DNA level, biochemists and immunologists are increasingly joined by molecular geneticists.
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Keratins and Other Epidermal Proteins
Skin Pigmentation and its Regulation
The Epidermal Basement Membrane
7 other sections not shown
abnormalities acne activity amino acid anchoring fibrils antibody antigen barrier basement membrane binding Biology cellular chains characterised chondroitin sulphate chromosome clinical cloning complex components connective tissue cross-linking culture cytokines dermal dermatan sulphate Dermatology dermis differentiation disorders domain drugs elastin enzyme epidermis epidermolysis bullosa extracellular matrix fatty acid fibrillin fibroblasts fibronectin function glands glycosaminoglycans GM-CSF growth factor hair follicle hemidesmosomes heparan sulphate heparan sulphate proteoglycan horny layer human skin hyaluronate identified increased inflammatory inhibits integrin interactions interleukin introns Investigative Dermatology Journal of Investigative keratin keratin genes keratinocytes lamina densa laminin lesions ligand lipids localised melanin melanocytes melanosomes metalloproteinases microfibrils molecular genetics molecules mutations normal patients pemphigoid pigmentation produce proliferation proteins proteoglycan psoriasis psoriatic receptors region regulation response retinoic acid retinoids role sebum sequence skin diseases specific steroids stimulate structural proteins syndrome synthesis T-cells TNFO tumour type I keratin type IV collagen tyrosinase VII collagen