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Treatment of neutropenia in patients undergoing cancer chemotherapy
Randomized phase II study with GMCSF and lowdose AraC
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ABMT acute leukaemia acute myeloid leukemia Aglietta allogenic antibiotic Ara-C autologous bone marrow blasts blood cell bone marrow transplantation Cancer Clin Oncol clinical clones colony cytokines cytotoxic disease dose double-blind drug Effect of recombinant Engl engraftment failure enhanced EORTC ganciclovir GM-CSF granulocyte colony-stimulating factor granulocyte-macrophage colony-stimulating factor growth factors Haematol haematological malignancies haematopoietic haematopoietic cells Hodgkin's human granulocyte-macrophage colony-stimulating increase infections infusion interleukin-3 kinetics low-dose AraC lymphoma macrophage and granulocyte macrophage colony-stimulating factor Medicine Services Limited megakaryocytes molgramostim Molgramostim GM-CSF myelodysplastic syndromes myeloid cells myeloid leukaemia N. C. Gorin neutropenia neutrophil neutrophil recovery normal patients receiving patients treated PBSCs placebo placebo controls platelet platelet counts possibilities and perspectives progenitor cells proliferation protein recombinant human granulocyte recombinant human granulocyte-macrophage refractory response rhGM-CSF Royal Society S-phase Sachs Society of Medicine stem cells stimulating factor survival therapy toxicity trial tumour versus vitro vivo