Mutagens and carcinogens in the diet: proceedings of a satellite symposium of the Fifth International Conference on Environmental Mutagens, held in Madison, Wisconsin, July 5-7, 1989, Volume 347
This comprehensive work explores a unique and often overlooked aspect of human cancer development and nutrition--namely, naturally occurring carcinogens in foods, focusing specifically on those associated with cooking or thermal processing. This book covers carcinogenicity of mutagens from cooked meats; dietary factors affecting spontaneous chromosomal damage in man; genotoxic mechanisms of fecapentaene-12 in human cells; antimutagenic/anticarcinogenic food components; updated legislative and regulatory perspectives from Japan, Europe and the U.S., and more.
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THERMALLY FORMED MUTAGENS AND CARCINOGENS
Metabolism and Biodisposition of Heterocyclic Amines
Preferential Activation and Genotoxicity of Food Derived Heterocyclic
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8-MeIQx aflatoxin AIA's amino acids animals anticarcinogenic antioxidant Ardex aromatic assay benzo[a]pyrene broiled Cancer Res Carcinogenesis carcinogens Chem chemical chromosomal compounds concentrations cooked creatine creatinine crypts cytochrome P-450 diet dietary dihydrodiol epoxide Dipple DMBA DNA damage dose effect enzymes epoxide erythrocytes factors fecapentaene-12 fecapentaenes Felton folate food additives food mutagens frequency gene genotoxicity glucose hepatitis hepatocellular carcinoma heterocyclic amines human hydrocarbons identified induced infected inhibition inhibitors isolated Jagerstad Kasai Knize levels limonene linoleic acid lipid peroxidation liver Maillard reaction mammalian cells mammary tumors meat MelQ MelQx metabolic activation metabolites mice micronucleated micronucleus microsomes model systems mouse Mspl mutagenesis mutagenic mutagenic activity mutagens and carcinogens Mutation Res mutations Nagao Natl Negishi Nutrition oxidants Pariza pesticide PhIP plasmid polycyclic protein pyrolysate rats risk Salmonella Sato sequence sesaminol Snyderwine soybean structure studies Sugimura Turesky vitro vivo Wakabayashi woodchucks