Neonatal Hematology: Pathogenesis, Diagnosis, and Management of Hematologic ProblemsPedro A. de Alarcón, Eric J. Werner, Robert D. Christensen, Martha C. Sola-Visner Neonatal hematology is a fast-growing field, and the majority of sick neonates will develop hematological problems. This is an essential guide to the pathogenesis, diagnosis and management of hematologic problems in the neonate. Guidance is practical, including blood test interpretation, advice on transfusions and reference ranges for hematological values. Chapters have been thoroughly revised according to the latest advances in the field for this updated third edition. Topics discussed include erythrocyte disorders, platelet disorders, leukocyte disorders, immunologic disorders and hemostatic disorders. Coverage of oncological issues has been expanded to two separate chapters on leukemia and solid tumors, making information more easily accessible. Approaches to identifying the cause of anemia in a neonate are explained, with detailed algorithms provided to aid clinicians in practice. Covering an important hematologic niche with an ever increasing amount of specialized knowledge, this book is a valuable resource for hematologists, neonatologists and pediatricians. |
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Contents
Functional Phagocyte Disorders in the Neonate 279 Section VIII Neonatal Oncology | 17 |
The Development of the Human Immune | 35 |
Immune Disorders | 43 |
Neonate | 62 |
Julie J KimChang James L Wynn 13 Acquired Thrombocytopenias | 210 |
Matthew A Saxonhouse and John Patricia E Davenport and Martha | 234 |
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abnormalities activity addition adult alloimmune anemia antibody antigen appear associated birth bleeding blood blood cell bone marrow cause Clin clinical common concentration congenital cord decreased defects deficiency diagnosis disease disorders dose early effects erythrocyte et al evaluation expression factor failure fetal findings function gene genetic gestation gestational age Hematol hematopoietic stem hemoglobin hemolysis hemolytic hemorrhage human identified immune immunodeficiency Immunol important incidence increased infants infections inherited initial iron less levels liver maternal months mothers mutations neonatal neutropenia neutrophil newborn normal observed occur outcome patients Pediatr period placenta plasma platelet platelet count pregnancy present preterm production protein rare reduced reported response risk screening severe sickle significant specific stem cells suggest syndrome T-cell Table term testing thalassemia therapy thrombocytopenia tion transfusion transplantation treated treatment tumors variants weeks