Networks of Innovation: Vaccine Development at Merck, Sharp and Dohme, and Mulford, 1895-1995
Cambridge University Press, Aug 13, 1997 - Business & Economics - 273 pages
Networks of Innovation offers an historical perspective on the manner in which private-sector organizations have acquired, sustained, and periodically lost the ability to develop, manufacture, and market new serum antitoxins and vaccines. The primary focus is on the H. K. Mulford Company, on Sharp and Dohme, which acquired Mulford in 1929, and upon Merck & Co Inc., which merged with Sharp and Dohme in 1953. By surveying a century of innovation in biologicals, the authors are able to analyze the conditions that either promoted or prevented creative changes in this important industry. They show how the activities of these three commercial enterprises were related to a series of complex, evolving networks of scientific, governmental, and medical institutions in the United States and abroad. This is the first such history to draw exclusively on sources internal to Merck, one of the world's leading innovators in modern vaccines and pharmaceuticals.
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A. A. McLean Adjuvant American Journal antibody antigen antitoxin bacteria biologicals Biology and Medicine Cell Biology clinical tests company's Control diphtheria doses Douglas drugs E. B. Buynak England Journal epidemic Experimental Biology firm firm's globulin Gordon Douglas H. K. Mulford Company Hepatitis B Vaccine History Human Hepatitis immunization industry infection Infectious Disease Journal influenza vaccine innovation Institute JAMA Jeryl Lynn Journal of Medicine Journal of Public Lancet licensed Live Attenuated long cycle M. R. Hilleman Magic Shots Marek's Disease Max Tishler Merck Merck Sharp MSDRL Mumps National Pediatrics percent pharmaceutical Philadelphia Pneumococcal Polysaccharide Vaccines pneumonia polio Poliomyelitis polysaccharide problems Public Health R. E. Weibel Rubella Vaccine Rubella Virus Vaccines scientific Scolnick serum Sharp & Dohme Society for Experimental Stokes strain tion United vaccine development Viral virology Virus and Cell Viruses Wagelos World Health Organization York
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