Neurobiology of Cocaine Addiction: A Reprint from "Science and Practice Perspectives"
DIANE Publishing, 2008 - 7 pages
Cocaine produces its psychoactive & addictive effects primarily by acting on the brain¿s limbic system, a set of interconnected regions that regulate pleasure & motivation. An initial, short-term effect -- a buildup of the neurochemical dopamine -- gives rise to euphoria & a desire to take the drug again. Researchers are seeking to understand how cocaine¿s many longer term effects produce addiction¿s persistent cravings & risk of relapse. This paper focuses on the buildup of the genetic transcription factor DeltaFosB in the limbic system which correlate with addiction-like behaviors in mice & may precipitate very long-lasting changes to nerve cell structure. This is one of the first steps toward an understanding of the transition from cocaine abuse to addiction.
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Alaska Native areas area measurements Area Outside Metropolitan Big Horn County BNA’s boundaries Carbon County Census Bureau census code Census designated place census tracts central city city of metropolitan concerning historical counts counted where larger County Square kilometers county subdivisions data products definitions of terms density designated place Number enumeration FIPS code Fremont County geographic areas Goshen County Housing Unit Counts Incorporated place Number Indian and Alaska Inside Metropolitan Area kilometers Square miles land area Laramie County MA’s MCD’s meanings of symbols metropolitan area Number METROPOLITAN AREA Total Natrona County Niobrara County nside urbanized area Number of places Place of less places Central city places Housing units places Population population and housing questionnaires sample Square kilometers __ Square kilometers Square statistical areas STF’s Sweetwater County tabulated where located terms and meanings town f U.S. Virgin Islands urban and rural urbanized area Place User Notes Washakie County Weston County
Page 16 - BG's generally contain between 250 and 550 housing units, with the ideal size being 400 housing units. Tabulation Block Group In the data tabulations, a geographic BG may be split to present data for every unique combination of county subdivision, place, American Indian and Alaska Native area, urbanized area, voting district...