New Research on Alzheimer's Disease

Front Cover
Nova Publishers, 2006 - Medical - 264 pages
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Dementia is a brain disorder that seriously affects a person's ability to carry out daily activities. The most common form of dementia among older people is Alzheimer's Disease (AD), which involves the parts of the brain that control memory, thought and language. Age is the most important known risk factor for AD. The number of people with the disease doubles every 5 years beyond age 65. AD is a slow disease, starting with mild memory loss and ending with severe brain damage. The course the disease takes and how fast changes occur vary from person to person. On average, AD patients live from 8 to 10 years after they are diagnosed, though the disease can last for as many as 20 years. Current research is aimed at understanding why AD occurs and who is at greatest risk for developing it, improving the accuracy of diagnosis and ability to identify who is at risk, developing, discovering and testing new treatments for behavioural problems in patients with AD. This book gathers state-of-the-art research from leading scientists throughout the world which offers important information on understanding the underlying causes and discovering the most effective treatments for Alzheimer's Disease.
 

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Contents

Insights on Alzheimers Disease from the Intracerebral Injection and Infusion of Amyloidβ
1
The Role of Phospholipase A₂ in Alzheimers Disease
57
Low Molecular Weight Glycosaminoglycans and Apoptosis Potential Treatment of Neurodegenerative Disorders Including Alzheimers Disease
87
Low Density Lipoprotein ReceptorRelated Protein 1 LRP1 One of the Hallmarks of Alzheimers Disease and Other Complex Degenerative Processes
99
The Role of Peroxisome ProliferatorActivated Receptors in Alzheimers Disease
125
Role of Sphingomyelin Cycle Signaling System in Alzheimers Disease
165
IschemiaReperfusion Factors in Sporadic Alzheimers Disease
183
Amyloid Beta Aβ Peptides in Plasma as Biochemical Markers of Alzheimers Disease and Mild Cognitive Impairment
235
Index
251
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