New Vaccine Development: Diseases of importance in the United States

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National Academies Press, 1985 - Medical - 458 pages
 

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Contents

Summary
1
A Review of Methods
17
Overview of the Analytic Approach
28
Comparison of Disease Burdens and Costs
39
Predictions on Vaccine Development
59
Assessing the Likely Utilization of New Vaccines
67
Calculation and Comparison of the Health Benefits and Costs Associated with Candidate Vaccines
92
Additional Issues in the Selection of Priorities for Accelerated Vaccine Development
121
F Prospects for Immunizing Against Hemophilus influenzae type b
235
G Prospects for Immunizing Against Hepatitis A Virus
252
H Prospects for Immunizing Against Hepatitis B Virus
261
Prospects for Immunizing Against Herpes Simplex Viruses 1 and 2
280
J Prospects for Immunizing Against Herpesvirus varicellae
313
K Prospects for Immunizing Against Influenza Viruses A and B
342
Prospects for Immunizing Against Neisseria gonorrhoeae
365
Prospects for Immunizing Against Parainfluenza Viruses
385

Findings Conclusions and Recommendations
127
APPENDIXES
128
A Some Examples of the Application of Project Selection Method
149
B Pathogenic Agents for Which Accelerated Vaccine Development Does Not Appear Appropriate
153
Prospects for Immunizing Against Bordetella pertussis
171
Prospects for Immunizing Against Coccidioidomycosis
183
E Prospects for Immunizing Against Cytomegalovirus
198
N Prospects for Immunizing Against Respiratory Syncytial Virus
397
O Prospects for Immunizing Against Rotavirus
410
P Prospects for Immunizing Against Streptococcus group B
424
Q Questionnaire for Assessing MorbidityMortality TradeOffs
440
T Additional Sources of Advice to the Committee
450
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