New Concepts in Immunodeficiency DiseasesRapid progress has been made in the understanding of the basic concepts of the immune response at biochemical and molecular levels. This text reviews the development of innovative techniques for diagnosing disorders at a very early stage and for detecting their carrier states and discusses novel therapeutic approaches such as gene therapy and the use of biological response modifiers. |
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Contents
Development of the Human Antibody Repertoire | 3 |
JOHN GORDON Department of Immunology The Medical School | 27 |
Their Potential Clinical Applications | 45 |
Copyright | |
16 other sections not shown
Common terms and phrases
Acad acid activation addition adhesion analysis antibody antigen appears associated binding Biol blood bone marrow cell activation cells chromosome chronic Clin clinical combined complement complex components contain cytoplasmic defect deficiency demonstrated described differentiation disease domain effects evidence expression factor fetal Figure function gene genetic glycosylation human immune immunodeficiency immunoglobulin Immunol important increase indicate individuals induce infections interaction involved kinase leukocyte levels lines linkage locus lymphocytes major mechanism mediated membrane MHC class molecular molecules mouse mutations NADPH Nature neutrophils normal observed oxidase pathway patients peripheral phosphorylation possible present Proc production proliferation protein rearrangement recent receptor region regulation repertoire reported response role segments selection sequence severe shown signal transduction specific stimulation structure studies suggest surface syndrome T-cell therapy tion transcription transplantation treatment tyrosine vitro
Bibliographic information
| Title | New Concepts in Immunodeficiency Diseases |
| Editors | Sudhir Gupta, Claude Griscelli |
| Edition | illustrated |
| Publisher | Wiley, 1993 |
| Original from | the University of Michigan |
| Digitized | Aug 7, 2008 |
| ISBN | 0471938807, 9780471938804 |
| Length | 518 pages |
| Subjects | › Health & Fitness / Allergies Medical / General |
| Export Citation | BiBTeX EndNote RefMan |