New Concepts in Immunodeficiency Diseases
Sudhir Gupta, Claude Griscelli
Wiley, Jun 8, 1993 - Health & Fitness - 518 pages
Rapid progress has been made in the understanding of the basic concepts of the immune response at biochemical and molecular levels. This text reviews the development of innovative techniques for diagnosing disorders at a very early stage and for detecting their carrier states and discusses novel therapeutic approaches such as gene therapy and the use of biological response modifiers.
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Development of the Human Antibody Repertoire
Pathways of Human B Cell Growth and Differentiation
Development of the Human T Cell Repertoire
16 other sections not shown
8MGuo Acad amino acids antibody antigen antigen receptor associated ataxia-telangiectasia binding Biol bone marrow Ca2+ cell activation cell lines cell receptor cell surface cellular CGD patients Chem chromosome chronic granulomatous disease Clin clinical clones combined immunodeficiency complex cytosolic defect deficiency differentiation domain endothelial expression factor fetal function gene segments genetic glycoprotein Griscelli human T cell IFNy IgA-D immu immune immunoglobulin Immunol immunological increase induce infections integrins interaction interleukin intracellular L-selectin ligand linkage locus lymphocytes mediated membrane MHC class mice molecular mouse mRNA murine mutations NADPH oxidase neutropenia neutrophils normal nucleotide pathway peripheral blood phagocytes phosphorylation polymorphic Proc production proliferation rearrangement region regulation repertoire response rhG-CSF role SCID sequence severe combined immunodeficiency signal transduction specific stem cells stimulation studies subunit T-cell therapy tion transcription tyrosine kinase tyrosine phosphorylation VH gene vitro vivo Wiskott-Aldrich syndrome X-linked XSCID