Academic Press, Dec 2, 2012 - Science - 384 pages
Nuclear Trafficking is a summary of the state of knowledge in nuclear trafficking, and is organized into five parts. The book begins by discussing the diffusion and signal-mediated transport through the pores. It then looks into the detailed accounts of pore structure and composition, nuclear localization signals, signal binding proteins, RNA efflux, and biochemical factors influencing nucleocytoplasmic exchange.
This book will be very useful to those people new to this field of interest.
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Acad accumulation adenovirus afﬁnity Agutter Akey amino acids antibodies antigen assembly Berrios binding Biochem Blobel cap structure Cell Biol components contain cytoplasmic diffusion Dingwall domain Drosophila efﬁciently eukaryotic export Feldherr ﬁlaments ﬁrst function gene Gerace GlcNAc glycoproteins Goldfarb histone hnRNA Identiﬁcation inﬂuence inhibit injected interactions intranuclear kinetics Lanford liver nuclei macromolecules mechanisms microinjected molecular molecules mRNA mRNA transport mutant myosin Natl Nature London Newmeyer NLSs NTPase nuclear envelope nuclear import nuclear localization signal nuclear matrix nuclear membrane nuclear pore complex nuclear pore proteins nuclear proteins nuclear transport nucleocytoplasmic transport nucleolar nucleoplasmin nucleoporins nucleus O-linked oocytes particles phosphorylation poly(A polypeptide pre-mRNA Proc protein import protein kinase rat liver regulation residues ribosomal proteins rRNA Scheer Schroeder sequence signal peptide snRNA snRNP speciﬁc spliceosome splicing studies substrate subunits sufﬁcient SV40-T signal transcription transport ligand tRNA virus vitro vivo Xenopus oocytes yeast