Obesity and Metabolism

Front Cover
Márta Korbonits
Karger Medical and Scientific Publishers, Jan 1, 2008 - Medical - 294 pages
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It has become increasingly difficult to keep up with the growing body of literature on the genetics, metabolic phenotype and treatment of obesity. This volume brings together an array of chapters from many of the foremost authorities and researchers in this area. Key advances in the genetics of obesity are summarized and the effects of obesity in pregnancy, childhood and old age explored. By scrutinizing the hormones and enzymes most recently implicated in the development, maintenance and consequences of obesity, the biochemical and physiological background of the abnormal metabolism of obesity is mapped out. Furthermore, a practical update on clinical approach and treatment of obesity is offered. Finally, the social aspects of obesity and the view of the obese body in art throughout the centuries are reflected. A valuable overview of causes, metabolic disturbances and treatment options, this volume will appeal to those with an interest in clinical as well as pathophysiological and genetic aspects of obesity. Furthermore, it will provide useful reading for scientists and students who would like to broaden and update their knowledge in this area.
 

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Contents

Monogenic Human Obesity
1
Genome Wide Strategies Reveal New Targets
12
Genetic Obesity Syndromes
37
Fetal and Neonatal Pathways to Obesity
61
The Role of Maternal Obesity
73
Childhood Obesity
85
Obesity in Old Age
97
Models of Obesity in Large Animals and Birds
107
Gut and Hormones and Obesity
165
Adipokines in Obesity
182
The Role of AMPActivated Protein Kinase in Obesity
198
Classical Endocrine Diseases Causing Obesity
212
Emerging Concepts in the Medical and Surgical Treatment of Obesity
229
The Sociology of Obesity
260
Obesity in Art A Brief Overview
271
Author Index
287

The BetaCell in Type 2 Diabetes and in Obesity
118
Role of the Endocannabinoid System in Energy Balance Regulation and Obesity
135
11 beta Hydroxysteroid Dehydrogenase Type 1 and Obesity
146

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