Omega-6/omega-3 Essential Fatty Acid Ratio: The Scientific Evidence

Front Cover
Artemis P. Simopoulos, Leslie G. Cleland
Karger Medical and Scientific Publishers, Jan 1, 2003 - Health & Fitness - 174 pages
Studies on the evolutionary aspects of diet and molecular studies included in this volume indicate that human beings evolved on a diet that was balanced in the essential fatty acids (EFA). In fact, the ratio of omega-6/omega-3 EFA was 1/1 whereas present day diets in both developed and developing countries have a much higher ratio, between 5/1 and 50/1. Additional studies show that a high ratio of omega-6/omega-3 EFA is detrimental to health and may lead to the development of chronic diseases. Improving the dietary ratio by decreasing the omega-6 fatty acids and increasing the omega-3 fatty acids is essential for brain function and for the management of cardiovascular disease, arthritis and cancer. A ratio of 4/1 or less leads to lower dosage and to the reduction of adverse effects of drugs. This volume should be of interest to a large and varied audience of researchers in academia, industry, and government; cardiologists, geneticists, immunologists, neuroscientists, and cancer specialists; as well as nutritionists, dietitians, food scientists, agriculturists, economists and regulators.
 

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Contents

The Importance of Omega6Omega3 Fatty Acid Ratio in Cell Function
23
Omega6Omega3 Ratio and BrainRelated Functions
37
Focus
57
Effects of an IndoMediterranean Diet on the Omega6Omega3
74
The Israeli Paradox
81
Linoleic Acid to AlphaLinolenic Acid Ratio From Clinical Trials to Inflammatory
92
The Japan Society for Lipid Nutrition Recommends to Reduce the Intake
109
Omega6Omega3 Polyunsaturated Fatty Acid Ratio and Cancer
133
Omega6Omega3 Fatty Acids and Arthritis
152
Author Index
169
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