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Amplification of Cellular Oncogenes in Tumor M Schwab K Alitolo H E Vormus Ond 245
csrc ond src Homolog Overexpression in D Sholloway P M Coussens and
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34-kD protein Acad amino acid analysis antigen assay avian sarcoma virus Biol Burkitt's lymphoma c-mos c-myc c-myc gene c-src Cancer carcinoma catalytic subunit cell lines cells transformed cellular chicken chromosome cloned codon containing culture deletion detected EcoRI encoded enzyme Erikson exon expression fibroblasts Figure fraction fragment function gene product genome growth factor Hanafusa homologous human hybridization immunoprecipitated incubated induced infected isolated J.M. Bishop labeled lane leukemia lymphoma middle T antigen middle T protein molecular monoclonal antibodies mouse mRNA murine mutants Natl normal nucleotide nucleotide sequence oncogene PDGF peptide phenotype phosphorylation phosphotyrosine plasmid polyoma virus probe Proc protein kinase activity provirus quences ras genes recombinant region retroviral Rous sarcoma virus serum shown specific splice src gene substrate tein trans transcription transfection transformed cells transforming gene transforming protein translocation tumor tyrosine phosphorylation v-myc v-src viral Virol virus-transformed viruses vitro