Osteoporosis: Pathophysiology and Clinical Management

Front Cover
Robert A. Adler
Springer Science & Business Media, Dec 14, 2009 - Medical - 636 pages

Osteoporosis is a widespread disorder with significant worldwide health and economic impact. In the second edition of the highly successful Osteoporosis: Pathophysiology and Clinical Management, new editor Robert A. Adler, MD, uses the same approach as the first edition, pairing a chapter on the basic science of a disorder followed by a chapter on its clinical aspects. Updated and expanded, this second edition includes many new chapters reflecting the growing literature on osteoporosis. New topics cover such areas as methods of bone imaging, screening for osteoporosis, adherence to therapy, and even a novel and exciting chapter on osteoporosis in men, to name just several. In Osteoporosis: Pathophysiology and Clinical Management, Second Edition, leading experts in a variety of fields have once again provided a wealth of invaluable, state-of-the-art information to illuminate the major scientific and clinical aspects of osteoporosis.

 

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Contents

1 Determinants of Peak Bone Mass Acquisition
1
Technical Aspects
23
3 New Imaging Techniques for Bone
51
4 The Clinical Role of Bone Density Scans in the Diagnosis and Treatment of Osteoporosis
77
5 Biochemical Markers of Bone Turnover Basic Biochemistry and Variability
97
6 Biochemical Markers of Bone Turnover Clinical Aspects
131
7 Biomechanics of Bone
157
8 Mechanical Influences on Bone Mass and Morphology
181
15 Estrogens and Estrogen AgonistsAntagonists
351
Basic Cellular and Molecular Aspects
359
Clinical Aspects
385
An Update on Its Clinical Utility in Osteoporosis
423
19 Bisphosphonate Mechanisms of Action
443
20 Bisphosphonates Treatment of Osteoporosis
469
21 Basic Aspects of PTH in Skeletal Health
487
22 Clinical Use of Parathyroid Hormone in Osteoporosis
511

9 Exercise in the Prevention of OsteoporosisRelated Fractures
207
10 The Physiology and Cell Biology of Calcium Transport in Relation to the Development of Osteoporosis
241
11 Calcium Bone and Life
269
12 Basic Aspects of Vitamin D Nutrition
301
13 Clinical Aspects of the Use of Vitamin D and Its Metabolites in Osteoporosis
319
14 The Basic Biology of Estrogen and Bone
333
23 Screening for Osteoporosis
527
24 Osteoporosis in Men
545
25 GlucocorticoidInduced Osteoporosis
559
26 Transplantation Osteoporosis
569
27 Adherence Compliance and Persistence with Osteoporosis Therapies
605
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