Paget's Disease of Bone: Clinical Assessment, Present and Future Therapy : Proceedings of the Symposium on the Treatment of Paget's Disease of Bone, Held October 20, 1989 in New York City
Frederick R. Singer, Stanley Wallach
Elsevier, 1991 - Medical - 313 pages
Paget's Disease of Bone: Clinical Assessment, Present and Future Therapy is a unique volume, the first of its kind, which details the latest information concerning all aspects of diagnosis and treatment of the disease. This disorder, a slow progressive diesase of the sketal system, was first identified more than one hundred years ago by Sir James Paget. For many years it was not fully understood or readily identified. Now, this one important volume brings together years of research and proven treatment methods.This important reference presents lucid discussions in many key areas including; the latest information about diagnosis and treatment, a thorough review of the drugs used to treat Paget's Disease, each detailed by a physician who was a pioneer in its use, comprehensive discussions of drugs which will be used in the future; approaches to management of Paget's Disease emphasizing indications for therapy and expected benefits, discussion of surgical treatment of Paget's Disease, reviews of diagnostic tests useful in the evaluation of Paget's Disease patients, the implication of diagnosis, management and treatment of the disease with the quickly expanding geriatric populations around the world. The lack of cohesive information available in the last several years has made Paget's Disease of Bone a significant and timely addition to the literature, providing answers and key information on progress made in the area. With the swelling proportions of geriatric populations worldwide, the demand for this information becomes even more urgent.Paget's Disease of Bone is an essential reference for all researchers and physicians in endocrinology, rheumatology, and orthopaedics as well as internists, family practice physicians and anyone involved with geriatric populations.
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50 IU tiw administration alkaline phosphatase activity alkaline phosphatase level Bijvoet OLM biochemical bisphosphonates bone formation Bone Mineral Res bone pain bone resorption bone turnover calcium cells Clin Orthop clinical resistance clodronate collagen courses of treatment decrease deformity diagnosis disease activity disease of bone dosage dose drug EHDP etidronate disodium femur Figure fractures hormone human calcitonin hydroxylysine hydroxyproline hypercalcemia increased initial value intranasal intravenous IU/d lesions long-term metabolic mg/d mg/kg/d mithramycin months Nagant de Deuxchaisnes nasal spray normal occur OHPU oral osteitis deformans osteoarthritis osteocalcin osteoclasts osteolytic osteoporosis Paget's disease Paget's Disease Foundation pagetic bone parenteral patients treated patients with Paget's peptides phonates plasma plicamycin radiographic radiologic remission response salmon calcitonin sarcoma SCT 50 IU SCT antibodies serum alkaline phosphatase side effects significant skeletal skull subcutaneous suppository suppression surfactant symptomatic symptoms therapeutic tibia tion treatment of Paget's tumors urinary hydroxyproline excretion