Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease MechanismsPathobiology of Human Disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. The work spans more than 48 different biological and medical fields, in five basic sections: Human - Organ Systems - Molecular Pathology/Basic Mechanisms of Diseases - Animal Models/Other Model Systems - Experimental Pathology - Clinical Pathology Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. - Reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting - Articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "Normal" and "Disease" anatomy and histology images - Fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions |
Contents
| 1 | |
Organ systems Pathophysiology | 753 |
Diagnostic Pathology | 3019 |
Techniques in Experimental Pathology | 3629 |
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Common terms and phrases
acid activation adaptive immune adhesion adipose tissue angiogenesis antibody antigen apoptosis apoptotic associated autoimmune autophagy binding Biol blood Ca2+ cancer cells caspases cell death cellular chemokines chromosome chronic clinical complement complex cytokines cytosol damage disease DNA methylation domain effector enzymes epigenetic expression Figure function gene genetic genome glucose histone human immune cells immune responses immune system Immunol increased induce infection inflammation inflammatory response inhibition inhibitors initial injury innate immune insulin resistance interaction intracellular involved kinase leptin leukocytes levels ligand lipid lymphocytes lysosomal macrophages mechanisms mediators membrane metabolic metastasis metastatic mice mitochondrial molecular molecules mutations myopathy necroptosis necrosis neoplasms neutrophils NF-kB obesity oxidative pathogens pathological patients peroxisomal phagocytes phenotype phosphorylation plasma production proinflammatory proliferation protein receptor recruitment regulation regulatory release role senescence sepsis specific studies syndrome synthesis T-cell target therapy tion toxins transcription factor trauma Tregs trigger tumor type 2 diabetes ubiquitin vascular