Pathophysiology, Pharmacology and Biochemistry of Dyskinesia

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Academic Press, Sep 7, 2011 - Medical - 664 pages
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Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia.



  • Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
 

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Contents

An Introduction to DyskinesiaThe Clinical Spectrum
1
lDopaInduced DyskinesiaClinical Presentation Genetics and Treatment
31
Experimental Models of lDOPAInduced Dyskinesia
55
Molecular Mechanisms of lDOPAInduced Dyskinesia
95
New Approaches to Therapy
123
Surgical Approach to lDopaInduced Dyskinesias
151
Clinical and Experimental Experiences of GraftInduced Dyskinesia
173
Clinical Presentation and Treatment
187
Clinical Presentation and Treatment
297
Genetics and Neuropathology of Huntingtons Disease
325
Pathogenic Mechanisms in Huntingtons Disease
373
Experimental Models of HD and Reflection on Therapeutic Strategies
419
CellBased Treatments for Huntingtons Disease
483
Clinical Phenomenology of Dystonia
509
Genetics and Pharmacological Treatment of Dystonia
525
Experimental Models of Dystonia
551

Epidemiology and Risk Factors for Tardive Dyskinesia
211
Genetics of Tardive Dyskinesia
231
Animal Models of Tardive Dyskinesia
265
Surgery for Tardive Dyskinesia
289
Surgical Treatment of Dystonia
573
Index
591
Contents of Recent Volumes
607
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