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A Brief Introduction to Human Genetics
Gene Identity by Descent
Estimating Relationships and Reconstructing Genealogies
7 other sections not shown
affected individuals allele frequencies alogy alternative autosomal locus carrier chapter chromosome common ancestors complex genealogies computation considered contributions core genealogy couple current population cutset denote dermatoglyphic descendants descent probabilities determined distribution double first cousins equation estimates example genealogy expected log-likelihood extinction founder genes function gene identity genealogical relationships genes in common genetic data genetic models geno genotype probabilities given half sibs HD/ID heterozygote Hodgkin's disease hypothesized identical genes identity by descent inbreeding independent inferences kinship coefficients large genealogies likelihood function linkage linked loci loci LOD score log-likelihood differences marginal likelihoods maximum likelihood method mother normal offspring original P(data pair parameters parent-offspring parents paternal gene pattern pedigree analysis phenotype phenotypic data polygenic possible prior probabilities proba proband problem quantitative trait random recombination reconstruction recursive relatives relevant rhesus sequential sibships single specified spouses Thompson tion triplets Tristan da Cunha values
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