Personalized Nutrition: Translating Nutrigenetic/nutrigenomic Research Into Dietary Guidelines

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Artemis P. Simopoulos, John A. Milner
Karger Medical and Scientific Publishers, 2010 - Medical - 180 pages
Awareness of the influence of our genetic variation to dietary response (nutrigenetics) and how nutrients may affect gene expression (nutrigenomics) is prompting a revolution in the field of nutrition. Nutrigenetics/Nutrigenomics provide powerful approaches to unravel the complex relationships among nutritional molecules, genetic variants and the biological system. This publication contains selected papers from the '3rd Congress of the International Society of Nutrigenetics/Nutrigenomics' held in Bethesda, Md., in October 2009. The contributions address frontiers in nutrigenetics, nutrigenomics, epigenetics, transcriptomics as well as non-coding RNAs and posttranslational gene regulations in various diseases and conditions. In addition to scientific studies, the challenges and opportunities facing governments, academia and the industry are included. Everyone interested in the future of personalized medicine and nutrition or agriculture, as well as researchers in academia, government and industry will find this publication of the utmost interest for their work.
 

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Contents

Opportunities and Challenges in NutrigeneticsNutrigenomics and Health
1
GenomeWide Association Studies and Diet
8
Copy Number Variation Eicosapentaenoic Acid and Neurological Disorders
15
A Tool to Provide Personalized Nutritional Therapy to the Obese
21
Xenobiotic Metabolizing Genes MeatRelated Exposures and Risk of Advanced Colorectal Adenoma
34
Strategies to Improve Detection of Hypertension Genes
46
Diet Nutrition and Modulation of Genomic Expression in Fetal Origins of Adult Disease
56
Clinical NutrigeneticNutrigenomic Approaches for Identification of Functions and Dietary Requirements
73
Changes in Human Adipose Tissue Gene Expression during DietInduced Weight Loss
103
Toxicogenomics and Studies of Genomic Effects of Dietary Components
115
Dietary Methyl Deficiency microRNA Expression and Susceptibility to Liver Carcinogenesis
123
Nutrigenetics as a Challenge in Psychiatric Disease Prevention
131
A Perspective
154
Building IndustryAcademia Partnerships
160
Opportunities for Collaboration
169
Author Index
176

Dietary Polyphenols Deacetylases and Chromatin Remodeling in Inflammation
84
Dietary Manipulation of Histone Structure and Function
95

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