Pharmaceutical Manufacturing EncyclopediaThis industry standard encyclopedia on pharmaceutical manufacturing processes has been completely updated to include FDA drugs approved up to the summer of 2004. The encyclopedia gives details for the manufacture of 2226 pharmaceuticals that are being marketed as a trade-named product somewhere in the world. Each entry includes:ò Therapeutic function ò Chemical and common nameò Structural Formulaò Chemical Abstracts Registry no.ò Trade name, manufacturer, country, and year introducedò Raw Materialsò Manufacturing ProcessIn addition, references are also cited under each drug's entry to major pharmaceutical works where additional information can be obtained on synthesis and the pharmacology of the individual products. |
Common terms and phrases
acetic acid acetone acid Manufacturing Process added dropwise alcohol ammonia aqueous solution Assigned benzene boiling bromide Chemical Abstracts Registry Chemical Name chloroform chromatography colorless column concentrated in vacuo cooled Country Year Introduced crude crystalline crystals diluted dimethylformamide distilled eluted ester ethanol ethyl acetate filtered flask France Germany grams heated hydride hydrochloric acid hydrochloride HYDROCHLORIDE Therapeutic Function hydrogen chloride Italy Japan Kleeman and Engel melting point methylene chloride mixture was stirred ml of methanol ml of water mmol mole Name Manufacturer Country nitrogen obtained OCDS Vol Patent Pharmaceutical potassium carbonate precipitate purified pyridine reaction mixture recrystallized reduced pressure References Merck Index reflux removed room temperature silica gel sodium bicarbonate sodium hydroxide sodium sulfate solid solvent Spain stirred at room Structural Formula suspension Switz tetrahydrofuran toluene Trade Name Manufacturer triethylamine vacuum washed with water yield ZYF Pharm Chemical