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Biopharmaceutics of Injectable Medication
Preformulation Research of Parenteral Medications
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acid agents ampuls antioxidants aqueous aseptic autoclave batch buffer Buffering agent CGMP chemical chloride clean room closures components compound compressed compressors concentration containers detergent and water determined distribution documentation dosage form drug product drug substance effect employees equipment evaluation facility Figure filling filter filtration floor fluid formulation freeze-drying glass heat HEPA intravenous labeling laminar flow liquid LVPs lyophilization manufacturing material membrane method microorganisms molecules operation oxidation packaging parenteral parenteral products particles performed personnel Pharm pharmaceutical phenytoin plastic polysorbate 80 powder prepared pressure problem procedures records remove reverse osmosis rinse rubber sample sanitation sealed Small Volume Parenteral sodium sodium chloride solubility solution solvent specific stability stainless steel steam sterile stopper storage surface suspension tank temperature testing tion tissue usually utilized vacuum valve vent vials washing Water for Injection