Physicochemical Principles of Pharmacy
The authors use pharmaceutical examples to illustrate the underlying physical chemistry of drug characterisation, formulation, delivery, transport, and absorption. Aimed at students of pharmacy, pharmaceutical science and medicinal chemistry. Third revised edition.
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Properties of the Solid State
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absorbed acetate acid activity adsorption aerosol agents anionic antacids aqueous phase aqueous solution base blood buffer calculated cationic cells cellulose cent chains chemical chemical potential chloride chlorpromazine colloidal complex component compounds concentration crystal crystalline decomposition decrease determined diffusion digoxin dilution dispersed dissolution dosage forms effect electrolytes emulsifiers emulsion equation equilibrium example figure film flocculation fluid formulation free energy glycol griseofulvin groups hydration hydrolysis hydrophilic hydrophobic increase injection insulin interaction interface intestine ionic ionisation ions layer lipid liquid macromolecules membrane micellar micelles mixture molar mole molecular weight particles partition coefficient pharm Pharmac pharmaceutical pilocarpine plasma plot polymer polymorphic properties protein binding Raoult's law rate constant reaction reduced reference resin salt shown sodium solid solubilisation solubility solvent stability structure substance sulphonamides surface tension surfactants suspension tablets temperature tetracycline unionised values viscosity volume Warfarin