Platelets, Thrombosis and the Vessel Wall

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Michael C Berndt
CRC Press, Sep 2, 2003 - Science - 356 pages
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Platelets, Thrombosis and the Vessel Wall aims to highlight the key areas of platelet function in the regulation of haemostasis and thrombosis and covers areas such as platelet production, interaction of platelets with leucocytes, mechanisms of cross-talk between platelets, leukocytes, and endothelium. The two major clinical causes of thrombosis, anti-phospholipid antibodies and genetic predisposition, are also addressed.
 

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Contents

1 Thrombopoietin
1
2 Platelets and Fibrinolysis
29
3 von Willebrand Factor and Platelet Adhesion
56
The Glycoprotein IbIXV Complex in Platelet Adhesion and Activation
88
5 The Platelet Glycoprotein IIbIIIa Complex
111
6 The Platelet Cytoskeleton
137
7 The Role of The PhosphoinositideDerived Second Messenger Molecules in Platelet Activation
169
8 The Biology of CD36
198
10 NeutrophilPlatelet Interactions
253
11 PSelectin
279
12 Role of PECAM1 in Vascular Biology
309
13 Role of Thrombospondins in Vascular Biology
338
Regulation of Gene Expression and Roles in Vascular Pathobiology
356
15 Antiphospholipid Antibodies
384
16 Resistance to Activated Protein C and Inherited ThrombosisMolecular Mechanism Diagnosis and Clinical Management
410
Subject Index
451

9 CD9 Structure and Function
230

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Baker Medical Research Institute, Commercial Road

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