Postoperative Nausea and Vomiting: A Practical GuideTong Joo Gan, Ashraf S. Habib Postoperative nausea and vomiting is an increasingly common and distressing problem faced by patients undergoing anesthesia that negatively affects their recovery and wellbeing and can result in significant increases in healthcare costs. Effective treatment strategies and relevant, up-to-date guidance are essential to manage postoperative nausea and vomiting in the perioperative setting. This practical, concise guide to the subject offers information on the history and mechanisms of postoperative nausea and vomiting, assessing and identifying risk factors, providing appropriate pharmacological and non-pharmacological treatment options, and implementing successful management strategies to tackle this issue. As a uniquely comprehensive study of the topic that provides much more detail than a chapter in a general anaesthesia textbook, this is an invaluable resource for anesthetists and physicians managing patients post-surgery. |
Contents
Mechanisms of nausea and vomiting | |
Risk factors and their impact on postoperative nausea | |
Patients experience and nursing perspective | |
Genomics and personalized medicine in postoperative | |
Pharmacology of serotonin antagonists | |
Tricia A Meyer and Russell K McAllister | |
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5HT3 antagonists 5HT3 receptor antagonists Acta Anaesthesiol Scand administration ambulatory surgery Anesth Analg anesthesia Anesthesiology anesthetic antiemetic antiemetic effect antiemetic efficacy Apfel CC aprepitant associated casopitant chemotherapyinduced nausea clinical clonidine combination compared costeffectiveness dexamethasone dimenhydrinate dolasetron dose doubleblind droperidol drug Eberhart LH emesis Gan TJ gene granisetron guidelines gynecologic halflife haloperidol incidence of PONV increased interventions intravenous Kranke laparoscopic management of postoperative metaanalysis metabolism metoclopramide mg/kg midazolam multimodal nausea and vomiting neurokinin NK1 receptor NK1 receptor antagonist NK1receptor antagonists ondansetron ondansetron 4 mg opioid oral palonosetron patients undergoing PDNV pediatric perioperative placebo polymorphism PONV PONV prophylaxis PONV risk postdischarge nausea postoperative nausea postoperative vomiting preventing PONV preventing postoperative nausea prevention of PONV prevention of postoperative prochlorperazine promethazine prophylactic antiemetic prophylaxis propofol randomized controlled trials RCTs reduced rescue antiemetic risk factors risk for PONV risk score scopolamine serotonin side effects systematic review treatment tropisetron versus