Practical Preimplantation Genetic Diagnosis"Preimplantation Genetic Diagnosis" (PGD) offers an answer in the control of inherited conditions by predicting reproductive outcome. PGD is no longer an experimental procedure, having become an integral part of genetic practices and assisted reproduction technology. Therefore this practical book will be vital for clinicians to access a comprehensive description of available experience, indications, methods, and clinical outcomes. The book describes the experience of PGD, demonstrating the considerable progress made in this revolutionary procedure and describing its utility within different patient groups, the accuracy of the laboratory methods, and prediction of the reproductive outcome. This will facilitate the use of PGD by practicing physicians, who may be able to offer patients this novel option for avoiding the birth of an affected child and having healthy children of their own. |
Contents
| 1 | |
Approaches to Preimplantation Genetic Diagnosis | 7 |
1 | 24 |
Mutations | 29 |
preimplantation Genetic Diagnosis for Single Gene Disorders | 37 |
Recessive Conditions 3 5 Conditions with No Available Direct Mutation Testing 3 6 LateOnset Disorders with Genetic Predisposition | 68 |