Practical Preimplantation Genetic Diagnosis

Front Cover
Springer Science & Business Media, Jan 16, 2006 - Medical - 198 pages

"Preimplantation Genetic Diagnosis" (PGD) offers an answer in the control of inherited conditions by predicting reproductive outcome. PGD is no longer an experimental procedure, having become an integral part of genetic practices and assisted reproduction technology. Therefore this practical book will be vital for clinicians to access a comprehensive description of available experience, indications, methods, and clinical outcomes.

The book describes the experience of PGD, demonstrating the considerable progress made in this revolutionary procedure and describing its utility within different patient groups, the accuracy of the laboratory methods, and prediction of the reproductive outcome. This will facilitate the use of PGD by practicing physicians, who may be able to offer patients this novel option for avoiding the birth of an affected child and having healthy children of their own.

 

Contents

Primary Prevention of Genetic Disorders and Place of Preimplantation
1
Preimplantation HLA Typing 4 1 PGD for Fanconi Anemia with Preimplantation
4
Approaches to Preimplantation Genetic Diagnosis
7
preimplantation Genetic Diagnosis for Single Gene Disorders
29
Recessive
55
14
95
29
103
59
109
Preimplantation Genetic Diagnosis for Chromosomal Disorders
135
Clinical Outcomes Following Preimplantation
171
Ethical Social and Legal Issues
189
Index
195
Copyright

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About the author (2006)

Yury Verlinksy and Anver Kuliev are two of the most respected names in the practice of perimplantation genetic diagnosis. Both work at the Reproductive Genetics Institute in Chicago, IL, USA, which is one of the most advanced and well-regarded medical institutions in the world in providing high quality services for infertility problems and genetic disorders.

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