Pregnancy and Birth After Assisted Reproductive Technologies

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Springer Science & Business Media, Aug 7, 2002 - Medical - 151 pages
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It is a pleasure to see this book in print. It represents work on an immense importance to assisted human conception. Numerous books have presented virtually every aspect of follicular growth, fertilization, male and female sterility and implantation.This is among the rare books dedicated to pr- nancy, birth and infant growth. Since the introduction of IVF, it has been clear that various problems could be associated with pregnancy after assisted human conception. The first clinical IVF pregnancy after the transfer of a 5-day blastocyst turned out to be ectopic, and this subjecthas neverbeen farfrom debates on the safety of assi- ed human conception ever since. Ectopic and heterotopic pregnancies were two factors stressed in early days of wor- wide IVF, and multiple pregnancies emerged as perhaps as an even more serious problem as high degrees of ovarian sti- lation began to be practised in some clinics. These chapters add the experience of the author, working in a large German IVF team, to discussions on these topics in this book.
 

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Contents

A Followup of Pregnancies in Assisted Reproduction Necessity and Problems
1
Why Is It Necessary to Perform a Followup of Pregnancies After an ART Procedure?
2
Why Do Not All Centres Perform a Followup of Pregnancies After an ART Procedure?
4
Conclusion
5
Incidence of Early Abortions and Ectopic Pregnancies in Assisted Reproduction
7
Incidence of Spontaneous Abortions
8
GIFT
12
FrozenThawed ET
15
Oocyte Donors
71
Followup of Oocyte Donors
72
Effects of Anonymity and Secrecy
74
Obstetric Outcome in Oocyte Donation Pregnancies
75
The Impact of Age
79
Conclusion
83
Congenital Malformations After ART
85
Congenital Malformations After IVF
86

Artificial Insemination with Donor Sperm AID
16
Incidence of Ectopic Pregnancies
17
Incidence of Heterotopic Pregnancies
20
Incidence of Disappearing Gestational Sacs
21
Incidence of Chromosomal Abnormalities in Abortions After Assisted Reproduction
25
Monosomy
26
Trisomy
27
Triploidy
28
Structural Chromosomal Anomalies
29
Effect of ICSI
30
Conclusion
31
Assisted Reproduction and Prenatal Diagnosis
33
ICSI and Prenatal Diagnosis
42
Noninvasive Prenatal Diagnosis
49
Ultrasound
50
Serum Markers for Prenatal Diagnosis
51
Conclusion
52
Obstetric Outcome of Pregnancies After Assisted Reproduction
55
Singleton Versus Multiple Pregnancies After IVF or IVFICSI
59
Versus Spontaneously Conceived Multiple Pregnancies
62
Higher Order Multiple Pregnancies Following ART
64
Descriptive Studies Without Control Groups
65
Conclusion
68
6 Oocyte Donation
69
Oocyte Recipients and Donors
70
Congenital Malformations After ICSI
88
Congenital Malformations After SUZI
94
Congenital Malformations After GIFT or Intrauterine Insemination
95
An Increased Risk for Certain Malformations
97
Alimentary Tract Atresia
98
Conclusion
99
Perinatal Outcome and Followup of Children Born from ART
101
Controlled Studies
102
Followup of Children From Cryopreserved Embryos
105
Conclusion
106
Development of Children of Lesbian Mothers After Using Assisted Reproduction Techniques
107
Gender Identity
108
Sexual Orientation
109
Other Aspects of Personality Development
110
Childrens Social Relationships
111
Children Conceived Via Donor Insemination by Lesbian Mothers
112
Conclusion
115
Development of Children and Family Structure After IVF and Gamete Donation
117
Children and Their Parents After Gamete Donation
121
Conclusion
124
General Conclusions
127
Abbreviation List
131
References
133
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