Preventive Pharmacotherapy of Headache Disorders

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Jes Olesen, Stephen D. Silberstein, Peer Tfelt-Hansen
Oxford University Press, 2004 - Medical - 276 pages
Most of the familiar headache drugs are used to stop a headache attack that is already in progress, or about to begin. However, there is now a growing body of research aimed at developing medications that can be taken on a regular basis to prevent headcahes from starting. These drugs will be targetted at patients whose headaches are frequent or who get their headaches at predicatble times. This book reviews the potential for prophylactic treatment of headache. It provides most of the existing evidence in the field of pharmaco-prophylaxis of migraine and other chronic headaches and may thus, serve as a platform for new initiatives in the field. The book reviews the research into the pharmacological mechanisms involved, the classes of drugs in development and the clinical trials methodology.The editors have gathered together the leading international experts to produce a book that will appeal neurologists caring for headache patients, researchers in the field and those based in the pharmaceutical industry.Readership: Neurologists and general physicians caring for headache patients, and all those with research interest in the field

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Principles of preventive pharmacotherapy in primary headache
Methodology and implementation of systematic reviews
Adverse events equally important as efficacy as an outcome parameter?

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About the author (2004)

Jes Olesen is in the Department of Neurology, Glostrup Hospital, University of Copenhagen, Denmark. Stephen D Silberstein is Director, Jefferson Headache Center, Thomas Jeffersen University, Philadelphia, Pennsylvania, USA. Peer Tfelt-Hansen is in the Department of Neurology, Glostrup Hospital, Denmark.

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