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analytic appear atherosclerosis Barren County blood pressure case-control studies Chap characteristics checkups cholesterol chronic cigarette smoking clinical cohort compared comparison control group coronary heart disease data analysis death rates described determine diagnosis differences disease occurrence distribution drug epidemic epidemiologic studies etiology Evaluation Evans County examination example experience experimental exposure factors findings fluoride follow-up Framingham Framingham Heart Study hospital hypertension important incidence rate incidence study infectious interview investigator involved low-back pain lung cancer measure methods mortality rates multiphasic multiphasic screening myocardial infarction observed occur osteoarthritis outcome particular patients pedestrians percent period persons physicians placebo poliomyelitis possible prevalence study preventive problems programs proportion quantitative quartile questions radiologists recorded relationship reported risk sample screening selected serum shown specific standard population stroke study population study subjects subgroup Table therapy tion treatment tuberculosis uric acid usually vaccine variables