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Features of biotechnology and its scientiﬁc basis
The biotechnology of enzyme isolation and puriﬁcation
Application of the principles of microbial genetics
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achieved activity agitation amino acids antibiotic aseptic auxotrophic bacteria batch biocatalyst biological biomass biosynthesis biotechnology bubbles chemical chrysogenum cloned coefﬁcient coli concentration constant containing cooling culture diameter difﬁcult diploid effect efﬁciency equation example feedback fermenter ﬁgure ﬁlamentous ﬁlm ﬁlter ﬁrst ﬂow ﬂow-rate ﬂuid ﬂuidized gene genetic glucose glutamate gramicidin growth medium growth rate haploid heat immobilized enzyme impeller increase industrial inhibition interferon involved isolated lac operon liquid maintained materials mechanical metabolism methanol microbial microorganisms molecular molecules mutants nutrient obtained operation organisms oxygen parameters parasexual cycle particles pathway penicillin penicillin production phage phase plant plasmid plug-ﬂow power input pressure primary metabolites protein protoplast puriﬁcation reaction reactor recombinant Reynolds number secondary metabolites selection sequence shear shear-rate signiﬁcant somatostatin sparging speciﬁc steam sterilization strain Streptomyces substrate sufﬁcient superﬁcial gas velocity synthesis temperature tetracycline transfer unit volume vector vessel viscosity waste-water yeast yield