Proceedings of the 14th International Symposium on Bioluminescence and Chemiluminescence: Chemistry, Biology and Applications, San Diego USA 15-19 October 2006In life science, bioluminescence and chemiluminescence have become a vital tool for laboratory analysis and biomedical imaging both in academic research and industrial product development. The latest advances in this exciting field, from fundamental research to cutting-edge applications, are explored in this most recent volume of the biannual symposium series, the Proceedings of the 14th International Symposium on Bioluminescence and Chemiluminescence.The volume highlights advances in fundamental knowledge about the origins and mechanisms of naturally occurring luminescence, including luciferases from firefly, beetle, marine, bacterial and fungal sources. Developments in instrumentation are presented, together with a wide variety of optical imaging applications for light-emitting gene expressions in optical imaging, such as imaging of gene expression and protein folding in cells, tissues and live animals. In particular, the various contributors describe in detail the use of light-emitting bacteria and viruses for the detection and therapy of tumors, as was highlighted in the symposium. |
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Contents
Refolding of the recombinant luciferases of Metridia longa | 3 |
Mechanistic study on the Cypridina Vargula bioluminescence | 11 |
Firefly luciferase arose from fatty acylCoA synthetase by gene | 19 |
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acid activity added addition aequorin allows analysis applications assay bacteria bacteriophages binding bioluminescence buffer cells Chem chemiluminescence choline coli compared compounds concentration constant containing culture decay decomposition dependence detection determined developed effect emission emitted enzyme experimental experiments expression firefly luciferase fluorescence function gene glucose human imaging increase incubation indicated induced infection intensity INTRODUCTION Japan levels light light emission live luciferase luciferin luminescence luminometer measured mechanism method mice milk molecular molecules monitoring mutants obelin observed obtained organic performed peroxide plasmid plate positive prepared presence probe promoter properties protein range reaction reagent REFERENCES reporter Research residues respectively response RESULTS AND DISCUSSION samples Science sensitivity sequence showed shown signal single solution solvents specific spectra stability standard structure Table tested transfected tumors University values yields