Progress in Systemic Lupus Erythematosus Research
This new book is devoted to leading-edge research developments in lupus which is a condition of chronic inflammation caused by an autoimmune disease. Autoimmune diseases are illnesses that occur when the body's tissues are attacked by its own immune system. The immune system is a complex system within the body that is designed to fight infectious agents, for example, bacteria, and other foreign invaders. One of the mechanisms that the immune system uses to fight infections is the production of antibodies. Patients with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. Because the antibodies and accompanying cells of inflammation can involve tissues anywhere in the body, lupus has the potential to affect a variety of areas of the body. Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved, the condition is called discoid lupus. When internal organs are involved, the condition is called systemic lupus erythematosus (SLE).
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COMORBIDITY IN SYSTEMIC LUPUS ERYTHEMATOSUS ASPECTS OF CARDIOVASCULAR DISEASE OSTEOPOROSIS AND INFECTIONS
SEVERE TISSUE TRAUMA TRIGGERS LUPUS AUTOIMMUNE DISEASE
IMMUNOTHERAPY WITH IGDERIVED PEPTIDES IN SLE CURRENT STATUS AND DIRECTIONS
AUTOANTIBODIES AS PROGNOSTIC OR DIAGNOSTIC MARKERS OF PSYCHIATRIC MANIFESTATIONS IN SLE
HIGHDOSE IMMUNOSUPPRESSION WITH AUTOLOGOUS STEM CELL TRANSPLANTATION IN SEVERE REFRACTORY SYSTEMIC LUPU...
abnormalities accelerated atherosclerosis anti-DNA antibodies anti-dsDNA anti-ribosomal antigens antiphospholipid antibodies Arthritis Rheum assessment associated atherosclerosis autoantibodies autoantigens autoimmune diseases blood brain burn injury cardiac cardiovascular disease cholesterol Circulation Clin clinical cohort complications coronary artery corticosteroids cyclophosphamide cytokines decrease demonstrated diastolic diffusion disease activity disorders dose dysfunction echocardiography effect endothelial cells endothelium epitopes evaluated fractures function gene imaging Immunol immunosuppressive drugs increased induced infections inflammation inflammatory inhibitors involvement lesions levels lipid lupus erythematosus SLE lupus nephritis lupus patients lupus-prone macrophages manifestations metabolic molecules mortality MRL/MpJ mice murine myocardial infarction myocarditis NPSLE osteoporosis pathogenesis patients with SLE patients with systemic peptide peripheral plasmapheresis polymorphisms pregnancy prevalence protein proteinuria pulmonary hypertension receptor renal response Rheum Rheumatol Rheumatology risk factors role serum sham-treated significant skin temperature SLE patients SSc group statins stem cell studies symptoms syndrome systemic lupus erythematosus therapeutic therapy tissue transplantation treatment Urowitz vascular vasculitis