Protecting the Frontline in Biodefense Research: The Special Immunizations Program

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National Academies Press, Jun 23, 2011 - Political Science - 184 pages
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The U.S. Army's Special Immunizations Program is an important component of an overall biosafety program for laboratory workers at risk of exposure to hazardous pathogens. The program provides immunizations to scientists, laboratory technicians and other support staff who work with certain hazardous pathogens and toxins. Although first established to serve military personnel, the program was expanded through a cost-sharing agreement in 2004 to include other government and civilian workers, reflecting the expansion in biodefense research in recent years. Protecting the Frontline in Biodefense Research examines issues related to the expansion of the Special Immunizations Program, considering the regulatory frameworks under which the vaccines are administered, how additional vaccines might be considered for inclusion in the Program, and factors that might influence the development and manufacturing of vaccines for the Special Immunizations Program.

 

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Contents

Summary
1
1 Introduction
7
2 History of the Special Immunizations Program and Lessons Learned from Occupational Immunization Against Hazardous Pathogens
21
3 The US Medical Countermeasures Enterprise and Recent Reviews and Current Operation of the Special Immunizations Program
43
4 Regulations and Other Guidance Pertaining to the Development and Use of Vaccines in the Special Immunizations Program
77
5 New Vaccine Development and the Future Needs of the Special Immunizations Program
95
6 Potential Options for the Special Immunizations Program and for Personnel Immunization
115
7 Conclusions and Recommendations
129
References
139
Appendixes
149
Committee Member Biographies
151
Abbreviations and Acronyms
159
Glossary
163
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