Proteins in Solution and at Interfaces: Methods and Applications in Biotechnology and Materials Science

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Juan M. Ruso, 聲gel Pi鎑iro
John Wiley & Sons, Jan 31, 2013 - Science - 500 pages
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Explores new applications emerging from our latest understanding of proteins in solution and at interfaces

Proteins in solution and at interfaces increasingly serve as the starting point for exciting new applications, from biomimetic materials to nanoparticle patterning. This book surveys the state of the science in the field, offering investigators a current understanding of the characteristics of proteins in solution and at interfaces as well as the techniques used to study these characteristics. Moreover, the authors explore many of the new and emerging applications that have resulted from the most recent studies. Topics include protein and protein aggregate structure; computational and experimental techniques to study protein structure, aggregation, and adsorption; proteins in non-standard conditions; and applications in biotechnology.

Proteins in Solution and at Interfaces is divided into two parts:

  • Part One introduces concepts as well as theoretical and experimental techniques that are used to study protein systems, including X-ray crystallography, nuclear magnetic resonance, small angle scattering, and spectroscopic methods
  • Part Two examines current and emerging applications, including nanomaterials, natural fibrous proteins, and biomolecular thermodynamics

The book's twenty-three chapters have been contributed by leading experts in the field. These contributions are based on a thorough review of the latest peer-reviewed findings as well as the authors' own research experience. Chapters begin with a discussion of core concepts and then gradually build in complexity, concluding with a forecast of future developments.

Readers will not only gain a current understanding of proteins in solution and at interfaces, but also will discover how theoretical and technical developments in the field can be translated into new applications in material design, genetic engineering, personalized medicine, drug delivery, biosensors, and biotechnology.


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XRay Crystallography of Biological
Nuclear Magnetic Resonance Methods
SmallAn le XRa Scatterin A lied
Resolving MembraneBound Protein
Investigating Protein Interactions at Solid
Proteins and Peptides in Biomimetic Polymeric
Study of Proteins and Peptides at Interfaces
A SingleMolecule Approach to Explore
Enhanced Functionality of Peroxidases By
Superactivity of Enzymes in Supramolecular
Surfactant Proteins and Natural Biofoams
Promiscuous Enzymes
Thermodynamics and Kinetics of Mixed

Calorimetric Methods to Characterize
Virtual Ligand Screening Against Comparative
Atomistic and CoarseGrained Molecular
Preparation of Nanomaterials Based
Natural Fibrous Proteins Structural Analysis
AmyloidLike Fibrils Origin Structure
Application of Force Spectroscopy Methods
Protein Gel Rheology
Exploring Biomolecular Thermodynamics

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About the author (2013)

JUAN M. RUSO is currently Associate Professor in the Department of Applied Physics at the University of Santiago de Compostela, Spain. He has contributed to more than 100 publications on a broad range of physical, chemical, and biophysics studies. His research interests include protein ligand interactions, thermal stabilization of protein, Phase behavior, and self-assembly processes in soft matter systems, biocompatible materials design, and nanocarrier design for targeted drug delivery.

篾GEL PI唎IRO is an IPP Research Fellow at the Department of Applied Physics of the University of Santiago de Compostela, Spain. His current research interests include the design and characterization of self-assembled systems as well as the study of macromolecules in solution, embedded in membranes or at interfaces. His work is mainly based on computational methods including multiscale molecular dynamics simulations and the development of software for the analysis of different experimental properties.

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