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THE INITIAL PSORIATIC LESION
CELL SURFACE ALTERATIONS
MITOCHONDRIAL ENZYMES IN PSORIASIS
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8-methoxypsoralen Acta Dermatovener activity agents antibodies arachidonic acid Arch Derm azaribine basal cancer capillary cell surface clinical corticosteroids Cox AJ Eds cyclic AMP Department of Dermatology dermal Dermatology dermis DHEA diabetes disease DNA synthesis dose drug effects enzyme epidermal cells epidermis erythema erythroderma exposure factors Farber Figure genetic glucocorticosteroids glycogen histological HL-A human hydroxyurea immunofluorescence increased inhibition Invest Derm involved irradiation joules/cm2 leukocytes levels liver biopsies lymphocytes mast cells Medical membrane metabolism methotrexate methoxsalen normal skin observed oral parakeratosis patients with psoriasis PGE2 Photochemotherapy present proliferation prostaglandin psoralen psoriasis vulgaris psoriatic arthritis psoriatic epidermis psoriatic lesions psoriatic patients psoriatic plaques psoriatic skin pustular psoriasis pustulosis PUVA treatment reaction response riasis SC antibodies SC antigens serum stratum corneum Table therapeutic therapy tion tissue topical treated treatment of psoriasis ultraviolet light uninvolved epidermis vitro vivo