Recent Advances in Quantitative Methods in Cancer and Human Health Risk AssessmentHuman health risk assessment involves the measuring of risk of exposure to disease, with a view to improving disease prevention. Mathematical, biological, statistical, and computational methods play a key role in exposure assessment, hazard assessment and identification, and dose-response modelling. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment is a comprehensive text that accounts for the wealth of new biological data as well as new biological, toxicological, and medical approaches adopted in risk assessment. It provides an authoritative compendium of state-of-the-art methods proposed and used, featuring contributions from eminent authors with varied experience from academia, government, and industry.
Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment will appeal to researchers and practitioners in public health & epidemiology, and postgraduate students alike. It will also be of interest to professionals working in risk assessment agencies. |
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Contents
I CANCER AND HUMAN HEALTH RISK ASSESSMENT Introductory remarks | 1 |
II BIOLOGICAL ASPECTS OF CARCINOGENESIS Introductory remarks | 25 |
III MODELING FOR CANCER RISK ASSESSMENT Introductory remarks | 111 |
IV STATISTICAL APPROACHES FOR CARCINOGENESIS STUDIES Introductory remarks | 193 |
V SPECIFIC MODELING APPROACHES FOR HEALTH RISK ASSESSMENT Introductory remarks | 281 |
Other editions - View all
Recent Advances in Quantitative Methods in Cancer and Human Health Risk ... Lutz Edler,Christos Kitsos No preview available - 2005 |
Recent Advances in Quantitative Methods in Cancer and Human Health Risk ... Lutz Edler,Christos Kitsos No preview available - 2005 |
Common terms and phrases
allele analysis animals applied approach Bayesian benchmark dose biological biomarkers Cancer and Human Cancer Research cancer risk carcinogenesis carcinogenic carcinoma cell chemical clinical cohort colorectal cancer components computed covariates data sets denotes described detection dioxin disease distribution dose groups dose levels dose-response curve dose-response models dose-response relationship Edler endometrial cancers endpoints environmental enzyme epidemiology evaluation example experimental exposure extrapolation factors foci function genes genetic genotype hazard Health Risk Assessment hormesis increased Kitsos lesions likelihood function linear liver logistic regression low-dose lung cancer malignant mathematical maximum likelihood metabolism Methods in Cancer mixture molecular Moolgavkar multistage model mutations NOAEL nonlinear observed obtained optimal design patients PBPK model polymorphisms population predict probability quantal radiation radiation hormesis random response risk assessment sample screening statistical stochastic studies TCDD threshold thyroid cancer tissue toxicity toxicokinetic Toxicology tumor uncertainty values variables xenobiotic