Rectal Cancer: International Perspectives on Multimodality Management

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Brian G. Czito, Christopher G. Willett
Springer Science & Business Media, Jul 29, 2010 - Medical - 316 pages
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Rectal Cancer: International Perspectives on Multimodality Management is a timely analysis of the diagnosis, staging, pathology, and therapy of cancer of the rectum. This book is intended as a useful resource for physicians, scientists, medical students, and allied health personnel in the disciplines of radiology, gastroenterology, surgical oncology, medical onc- ogy, radiation oncology, and pathology. Renowned contributors from different medical d- ciplines have written their chapters in a thoughtful, provocative, and visual fashion. Importantly, these chapters highlight the controversies in the diagnostic, staging, and the- peutic management of patients with rectal cancer while providing practical management recommendations. This book is divided into 18 chapters. Early chapters address the diagnosis and staging of rectal cancer, highlighting the critical role of contemporary imaging in guiding treatment. The remaining chapters focus on the multimodality management of rectal cancer from the vantage points of surgery, pathology, chemotherapy, and radiation therapy. The major dev- opments in surgery are reviewed first, including contemporary roles of local excision, total mesorectal excision, lateral pelvic lymph node dissection, organ preservation approaches, as well as the management of advanced, recurrent, and metastatic disease. Following is a ch- ter describing the pathologic evaluation of rectal cancer specimens, with emphasis on proper methodology and its clinical relevance to overall disease management. The final chapters review the contemporary roles of chemotherapy (including with radiation therapy, adjuvant and neoadjuvant settings without radiation therapy, as well as in metastatic disease) as well as radiation therapy (including adjuvant and neoadjuvant approaches, short vs.
 

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Contents

Clinical Staging Endoscopic Techniques
1
Clinical Staging CT and MRI
21
Local Excision
37
Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection
53
Abdominoperineal Resection Low Anterior Resection and Beyond
79
T4 and Recurrent Rectal Cancer
109
Surgical Management of Pulmonary Metastases
122
Surgical and Ablative Management of Liver Metastases
129
Chemotherapy Adjuvant and Neoadjuvant Approaches
175
Chemotherapy Metastatic Disease
189
Radiation Therapy Adjuvant vs Neoadjuvant Therapy
223
Radiation Therapy Short Versus Long Course
235
Chemoradiation Therapy Nonoperative Approaches
249
Contact XRay Therapy
267
HighDoseRate Preoperative Endorectal Brachytherapy for Patients with Rectal Cancer
277
Radiation Therapy Technical Innovations
289

Surgical Pathology
151
Chemotherapy Concurrent Delivery with Radiation Therapy
165

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