Response of Hypotensive Dogs to Dopamine and Dobutamine Under Deep Isoflurane Anesthesia

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University of Guelph, 2007 - 184 pages
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This thesis is an investigation of the individual and combined dose response of dopamine and dobutamine in the deeply isoflurane-anesthetized dog. The objective was to evaluate the dose related cardiovascular and urine output (UrO) effects of dopamine (Dp) and dobutamine (Db), individually and in combination in the dog under deep isoflurane anesthesia. To identify individual doses able to achieve a target mean arterial blood pressure (MAP) (70 mm Hg) and cardiac index (CI) (150 ml/kg/min) as well as assess ratios of these doses in combination.

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